From genetic data to clinical insights. Automatically.

Toll-like receptor 4-mediated cytokine synthesis and post-stroke depressive symptoms - bioinformatics analysis of RNA-seq

Task/Hypothesis: to explore the putative association between TLR4-mediated cytokine synthesis and subsequent symptoms of PSD.

Transcriptional alterations of prefrontal cortex astrocytes in a subpopulation of suicide completers - bioinformatics analysis of nuclei RNAseq

Task/Hypothesis: changes in the molecular profile of astrocytes may underlie metabolic reprogramming.

Identification of possibly pathogenic variants likely contributing to the risk of Gilles de la Tourette syndrome (GTS) and spectrum of tic disorders (TDs)

Problem/Task: the construction of an oligogenic risk model of GTS based on possibly pathogenic variants likely contributing to the risk of GTS and TDs.

Identification of the genetic variants contributing to the early-onset semantic dementia phenotype

Due to the overlapping clinical presentations and neuropathology, clinical diagnosis of dementia is frequently challenging and inconclusive. The use of next-generation sequencing methods revealed the complex genomic nature of disease phenotypes, shifting the pathogenicity model from monogenic to oligogenic inheritance.

Collaboration with ixLayer for Vitalleo

ixLayer is a US-based company that creates a complete solution for Health Testing by removing all the technical, security, and regulatory complexity involved in launching clients’ programs quickly and efficiently. This process provides a complete set of building blocks that enables leading health systems, clinical labs, biopharma, and consumer companies to offer precision health testing.

Cooperation with Adamed during MIT Enterprise Forum CEE acceleration program

In 2019, we got to the finals of the MITEF Central Eastern Europe acceleration program. MITEF CEE is a part of the global network of MIT Enterprise Forum, affiliated with the world’s best technology university – the Massachusetts Institute of Technology.

Transcriptomic research collaboration with BioMed X Institute

We have entered into cooperation with the independent research institute BioMed X that performs biomedical preclinical research projects in the fields of biomedicine, molecular biology, cell biology, and diagnostics.

Collaboration with Boehringer Ingelheim on the project dedicated to central nervous system diseases

The long-range goal of the study was to verify the usability of the Fkbp5 × ELA (early life adversity) mouse model for further investigation of the Fkbp5 gene variants influence on the resilience to stress. Single nucleotide polymorphisms (SNPs) in the human FKBP5 gene were previously shown to modulate the risk of stress-related disorders.

NGS pipeline development in cooperation with SCC Soft Computers

In 2019, we established cooperation with one of the largest LIS programming houses in the world SCC Soft Computers...

Partnership with Helix

In 2017, we have developed the MyTraits Sport mobile application – a translation of human genome into a personalized analysis of fitness-related traits. The app is available on the Helix marketplace for direct-to-consumer DNA-powered products.